5-chloro-1H-indole-3-carbaldehyde → HCID 58981100, compound

HRID 1181818Notes

Reaction equation

HRID 1181818 reaction equation
[NH:1]([C:3]1[N:8]([CH2:9][CH:10]([CH3:12])[CH3:11])[C:7](=[O:13])[N:6]([CH3:14])[C:5](=[O:15])[CH:4]=1)[NH2:2].[Cl:16][C:17]1[CH:18]=[C:19]2[C:23](=[CH:24][CH:25]=1)[NH:22][CH:21]=[C:20]2[CH:26]=O.[C:28]([C:33]1[N:34]=[C:35]([CH:39]=O)[N:36]([CH3:38])[CH:37]=1)(=[O:32])[CH:29]([CH3:31])[CH3:30]>>[Cl:16][C:17]1[CH:18]=[C:19]2[C:23](=[CH:24][CH:25]=1)[NH:22][CH:21]=[C:20]2[CH2:26][N:2]1[C:39]([C:35]2[N:36]([CH3:38])[CH:37]=[C:33]([C:28](=[O:32])[CH:29]([CH3:31])[CH3:30])[N:34]=2)=[C:4]2[C:3]([N:8]([CH2:9][CH:10]([CH3:11])[CH3:12])[C:7](=[O:13])[N:6]([CH3:14])[C:5]2=[O:15])=[N:1]1

Participants

4

Reactant 3

HCID 27953745-chloro-1H-indole-3-carbaldehydeHCID 193560846-hydrazino-1-isobutyl-3-methyl-2,4(1H,3H)-pyrimidinedioneHCID 86595434HCID 86595434, compound

Product 1

HCID 58981100HCID 58981100, compound

Procedure

This compound was made following the procedure described above, starting with 6-hydrazino-1-isobutyl-3-methylpyrimidine-2,4(1H,3H)-dione, and condensing first 5-chloro-1H-indole-3-carbaldehyde, followed by 4-isobutyryl-1-methyl-1H-imidazole-2-carbaldehyde. 536 (M+H).

Sources & evidence

ORD record
ord-9a4bbe42ccf34c79829e9a1dc1a62e52
Source dataset
uspto-grants-2007_10
Patent number
US07285558B2

Reaction notes

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