1-Methyl-1H-pyrrole-2-carbaldehyde → HCID 58981175, compound

HRID 1181823Notes

Reaction equation

HRID 1181823 reaction equation
[NH:1]([C:3]1[N:8]([CH2:9][CH:10]([CH3:12])[CH3:11])[C:7](=[O:13])[N:6]([CH3:14])[C:5](=[O:15])[CH:4]=1)[NH2:2].[Cl:16][C:17]1[CH:18]=[C:19]2[C:24](=[CH:25][CH:26]=1)[N:23]=[CH:22][CH:21]=[C:20]2[CH:27]=O.[CH3:29][N:30]1[CH:34]=[CH:33][CH:32]=[C:31]1[CH:35]=O>>[Cl:16][C:17]1[CH:18]=[C:19]2[C:24](=[CH:25][CH:26]=1)[N:23]=[CH:22][CH:21]=[C:20]2[CH2:27][N:2]1[C:35]([C:31]2[N:30]([CH3:29])[CH:34]=[CH:33][CH:32]=2)=[C:4]2[C:3]([N:8]([CH2:9][CH:10]([CH3:11])[CH3:12])[C:7](=[O:13])[N:6]([CH3:14])[C:5]2=[O:15])=[N:1]1

Participants

4

Reactant 3

HCID 145041-Methyl-1H-pyrrole-2-carbaldehydeHCID 31460316-Chloroquinoline-4-carbaldehydeHCID 193560846-hydrazino-1-isobutyl-3-methyl-2,4(1H,3H)-pyrimidinedione

Product 1

HCID 58981175HCID 58981175, compound

Procedure

This compound was made following the procedure described above, starting with 6-hydrazino-1-isobutyl-3-methylpyrimidine-2,4(1H,3H)-dione, and condensing first with 6-chloroquinoline-4-carbaldehyde, followed by 1-methyl-1H-pyrrole-2-carbaldehyde. 477.9 (M+H).

Sources & evidence

ORD record
ord-c8dc6679ab7842bf8984cdcfe4f491b2
Source dataset
uspto-grants-2007_10
Patent number
US07285558B2

Reaction notes

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