6-hydrazino-1-isobutyl-3-methyl-2,4(1H,3H)-pyrimidinedione → HCID 58981070, compound

HRID 1181826Notes

Reaction equation

HRID 1181826 reaction equation
[NH:1]([C:3]1[N:8]([CH2:9][CH:10]([CH3:12])[CH3:11])[C:7](=[O:13])[N:6]([CH3:14])[C:5](=[O:15])[CH:4]=1)[NH2:2].[F:16][C:17]1[CH:18]=[C:19]2[C:24](=[CH:25][CH:26]=1)[N:23]=[CH:22][CH:21]=[C:20]2[CH:27]=O.[CH3:29][N:30]1[CH:34]=[C:33]([C:35](=[O:38])[CH2:36][CH3:37])[CH:32]=[C:31]1[CH:39]=O>>[F:16][C:17]1[CH:18]=[C:19]2[C:24](=[CH:25][CH:26]=1)[N:23]=[CH:22][CH:21]=[C:20]2[CH2:27][N:2]1[C:39]([C:31]2[N:30]([CH3:29])[CH:34]=[C:33]([C:35](=[O:38])[CH2:36][CH3:37])[CH:32]=2)=[C:4]2[C:3]([N:8]([CH2:9][CH:10]([CH3:11])[CH3:12])[C:7](=[O:13])[N:6]([CH3:14])[C:5]2=[O:15])=[N:1]1

Participants

4

Reactant 3

HCID 193560846-hydrazino-1-isobutyl-3-methyl-2,4(1H,3H)-pyrimidinedioneHCID 20110104HCID 20110104, compoundHCID 36688027HCID 36688027, compound

Product 1

HCID 58981070HCID 58981070, compound

Procedure

This compound was made following the procedure described above, starting with 6-hydrazino-1-isobutyl-3-methylpyrimidine-2,4(1H,3H)-dione, and condensing first with 6-fluoroquinoline-4-carbaldehyde, followed by 1-methyl-4-propionyl-1H-pyrrole-2-carbaldehyde. 517 (M+H).

Sources & evidence

ORD record
ord-8c4f2eeb35d94538afa32da0f1683372
Source dataset
uspto-grants-2007_10
Patent number
US07285558B2

Reaction notes

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