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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1181832Generated: October 25, 2026

1-Ethyl-2-pyrrolecarboxaldehyde → 2-[(5-chloro-1H-indol-3-yl)methyl]-3-(1-ethyl-1H-pyrrol-2-yl)-7-isobutyl-5-methyl-2H-pyrazolo[3,4-d]pyrimidine-4,6(5H,7H)-dione

https://huagongshe.com/reaction/1181832

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-Ethyl-2-pyrrolecarboxaldehydeHCID 579338—
Reactant5-chloro-1H-indole-3-carbaldehydeHCID 2795374—
Reactant6-hydrazino-1-isobutyl-3-methyl-2,4(1H,3H)-pyrimidinedioneHCID 19356084—
Product2-[(5-chloro-1H-indol-3-yl)methyl]-3-(1-ethyl-1H-pyrrol-2-yl)-7-isobutyl-5-methyl-2H-pyrazolo[3,4-d]pyrimidine-4,6(5H,7H)-dioneHCID 58981035—

Reaction Steps

This compound was made following the procedure described above, starting with 6-hydrazino-1-isobutyl-3-methylpyrimidine-2,4(1H,3H)-dione and condensing first with 5-chloro-1H-indole-3-carbaldehyde, followed by 1-ethyl-1H-pyrrole-2-carbaldehyde. 479 (M+H).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07285558B2
Source datasetuspto-grants-2007_10
ORD IDord-cc2efaa07f084ae29a3511a50584f671
Source noteuspto-grants-2007_10