4-Acetyl-1-methyl-1H-pyrrole-2-carbaldehyde → HCID 58981115, compound

HRID 1181833Notes

Reaction equation

HRID 1181833 reaction equation
[NH:1]([C:3]1[N:8]([CH2:9][CH:10]([CH3:12])[CH3:11])[C:7](=[O:13])[N:6]([CH3:14])[C:5](=[O:15])[CH:4]=1)[NH2:2].[F:16][C:17]([F:31])([F:30])[C:18]1[CH:19]=[C:20]2[C:25](=[CH:26][CH:27]=1)[N:24]=[CH:23][CH:22]=[C:21]2[CH:28]=O.[CH3:32][N:33]1[CH:37]=[C:36]([C:38](=[O:40])[CH3:39])[CH:35]=[C:34]1[CH:41]=O>>[C:38]([C:36]1[CH:35]=[C:34]([C:41]2[N:2]([CH2:28][C:21]3[C:20]4[C:25](=[CH:26][CH:27]=[C:18]([C:17]([F:31])([F:30])[F:16])[CH:19]=4)[N:24]=[CH:23][CH:22]=3)[N:1]=[C:3]3[C:4]=2[C:5](=[O:15])[N:6]([CH3:14])[C:7](=[O:13])[N:8]3[CH2:9][CH:10]([CH3:11])[CH3:12])[N:33]([CH3:32])[CH:37]=1)(=[O:40])[CH3:39]

Participants

4

Reactant 3

HCID 126762684-Acetyl-1-methyl-1H-pyrrole-2-carbaldehydeHCID 193560846-hydrazino-1-isobutyl-3-methyl-2,4(1H,3H)-pyrimidinedioneHCID 233621156-(Trifluoromethyl)quinoline-4-carbaldehyde

Product 1

HCID 58981115HCID 58981115, compound

Procedure

This compound was made following the procedure described above, starting with 6-hydrazino-1-isobutyl-3-methylpyrimidine-2,4(1H,3H)-dione, and condensing first with 6-trifluoromethylquinoline-4-carbaldehyde, followed by 1-methyl-4-acetyl-1H-pyrrole-2-carbaldehyde. 553(M+H).

Sources & evidence

ORD record
ord-6ec1cae7fa604c5595fd553de51fa5dd
Source dataset
uspto-grants-2007_10
Patent number
US07285558B2

Reaction notes

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