6-hydrazino-1-isobutyl-3-methyl-2,4(1H,3H)-pyrimidinedione → HCID 58981182, compound

HRID 1181834Notes

Reaction equation

HRID 1181834 reaction equation
[NH:1]([C:3]1[N:8]([CH2:9][CH:10]([CH3:12])[CH3:11])[C:7](=[O:13])[N:6]([CH3:14])[C:5](=[O:15])[CH:4]=1)[NH2:2].[F:16][C:17]([F:31])([F:30])[C:18]1[CH:19]=[C:20]2[C:25](=[CH:26][CH:27]=1)[N:24]=[CH:23][CH:22]=[C:21]2[CH:28]=O.[CH3:32][N:33]1[CH:37]=[C:36]([C:38](=[O:41])[CH2:39][CH3:40])[CH:35]=[C:34]1[CH:42]=O>>[CH2:9]([N:8]1[C:3]2=[N:1][N:2]([CH2:28][C:21]3[C:20]4[C:25](=[CH:26][CH:27]=[C:18]([C:17]([F:31])([F:30])[F:16])[CH:19]=4)[N:24]=[CH:23][CH:22]=3)[C:42]([C:34]3[N:33]([CH3:32])[CH:37]=[C:36]([C:38](=[O:41])[CH2:39][CH3:40])[CH:35]=3)=[C:4]2[C:5](=[O:15])[N:6]([CH3:14])[C:7]1=[O:13])[CH:10]([CH3:11])[CH3:12]

Participants

4

Procedure

This compound was made following the procedure described above, starting with 6-hydrazino-1-isobutyl-3-methylpyrimidine-2,4(1H,3H)-dione, and condensing first with 6-trifluoromethylquinoline-4-carbaldehyde, followed by 1-methyl-4-propionyl-1H-pyrrole-2-carbaldehyde. 567(M+H).

Sources & evidence

ORD record
ord-2b1c6a5e653c4586ade45602a78b40fd
Source dataset
uspto-grants-2007_10
Patent number
US07285558B2

Reaction notes

Loading…