HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Methyl-2-imidazolecarboxaldehyde → 7-(cyclopropylmethyl)-5-methyl-3-(1-methyl-1H-imidazol-2-yl)-2-{[5-(trifluoromethyl)-1H-indol-3-yl]methyl}-2H-pyrazolo[3,4-d]pyrimidine-4,6(5H,7H)-dione
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Methyl-2-imidazolecarboxaldehyde | HCID 139575 | — |
| Reactant | 5-(Trifluoromethyl)-1h-indole-3-carbaldehyde | HCID 28984879 | — |
| Reactant | 1-(cyclopropylmethyl)-6-hydrazino-3-methylpyrimidine-2,4(1H,3H)-dione | HCID 69427171 | — |
| Product | 7-(cyclopropylmethyl)-5-methyl-3-(1-methyl-1H-imidazol-2-yl)-2-{[5-(trifluoromethyl)-1H-indol-3-yl]methyl}-2H-pyrazolo[3,4-d]pyrimidine-4,6(5H,7H)-dione | HCID 58981094 | — |
Reaction Steps
This compound was made following the procedure described above, starting with 1-(cyclopropylmethyl)-6-hydrazino-3-methylpyrimidine-2,4(1H,3H)-dione, and condensing first with 5-(trifluoromethyl)-1H-indole-3-carbaldehyde, followed by 1-methyl-1H-imidazole-2-carbaldehyde. 498.2 (M+H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07285558B2 |
| Source dataset | uspto-grants-2007_10 |
| ORD ID | ord-1f032741360549d0a99148db72081df1 |
| Source note | uspto-grants-2007_10 |