4-(2-Chloroethyl)morpholine → 2-[(6-chloroquinolin-4-yl)methyl]-7-isobutyl-3-(4-methyl-4H-1,2,4-triazol-3-yl)-5-(2-morpholin-4-ylethyl)-2H-pyrazolo[3,4-d]pyrimidine-4,6(5H,7H)-dione

Participants

Role	Name	HCID	Charge
Reactant	4-(2-Chloroethyl)morpholine	HCID 76727	—
Reactant	2-[(6-chloroquinolin-4-yl)methyl]-7-isobutyl-3-(4-methyl-4H-1,2,4-triazol-3-yl)-2H-pyrazolo[3,4-d]pyrimidine-4,6(5H,7H)-dione	HCID 58981083	—
Product	2-[(6-chloroquinolin-4-yl)methyl]-7-isobutyl-3-(4-methyl-4H-1,2,4-triazol-3-yl)-5-(2-morpholin-4-ylethyl)-2H-pyrazolo[3,4-d]pyrimidine-4,6(5H,7H)-dione	HCID 58981162	—

Reaction Steps

This compound was made by alkylation of 2-[(6-chloroquinolin-4-yl)methyl]-7-isobutyl-3-(4-methyl-4H-1,2,4-triazol-3-yl)-2H-pyrazolo[3,4-d]pyrimidine-4,6(5H,7H)-dione with 4-(2-chloroethyl)morpholine following conditions in Example 6.d. 578.2 (M+H).

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US07285558B2
Source dataset	uspto-grants-2007_10
ORD ID	ord-c8fe0d8c96d5430383812192988945e0
Source note	uspto-grants-2007_10