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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 118184Generated: October 26, 2026

Bromide ion → Methyl 3-difluoromethoxy-thiophene-2-carboxylate

https://huagongshe.com/reaction/118184

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBromide ionHCID 259—
ReactantSodium ionHCID 923—
ReactantHydroxideHCID 961—
ReactantWaterHCID 962—
ReactantTolueneHCID 1140—
ReactantChlorodifluoromethaneHCID 6372—
ReactantTetrabutylphosphonium cationHCID 75312—
Reactant3-Hydroxy-thiophene-2-carboxylic acid methyl esterHCID 581127—
ProductMethyl 3-difluoromethoxy-thiophene-2-carboxylateHCID 15376481—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (2/10)
ORD IDord-d9a3cfd90788413bb169c2f8b9126924
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (2/10)