Acetic Anhydride → HCID 68495340, compound

HRID 1182021Notes

Reaction equation

HRID 1182021 reaction equation
C(OC(=O)C)(=O)C.[Br:8][C@@:9]1([O:23][C@H:22]([CH2:24][O:25][C:26](=[O:28])[CH3:27])[C@@H:21]([F:29])[C@H:16]([O:17][C:18](=[O:20])[CH3:19])[C@H:11]1[O:12][C:13](=[O:15])[CH3:14])[OH:10]>N1C=CC=CC=1>[Br:8][C@@:9]1([O:23][C@H:22]([CH2:24][O:25][C:26](=[O:28])[CH3:27])[C@H:21]([F:29])[C@H:16]([O:17][C:18](=[O:20])[CH3:19])[C@H:11]1[O:12][C:13](=[O:15])[CH3:14])[OH:10]

Participants

4

Reactant 2

HCID 7918Acetic AnhydrideHCID 68492273HCID 68492273, compound

Product 1

HCID 68495340HCID 68495340, compoundYield 44%

Reagents, catalysts & solvents 1

HCID 1049PyridineSolvent

Procedure

100 mg (0.55 mmol) of 3 are reacted with 3.5 ml of pyridine and 3.5 ml of acetic anhydride in analogy to the preparation of compound 2. 89 mg (44%) of 4 are obtained as an amorphous solid.

Sources & evidence

ORD record
ord-d1f3237de5884e51aff69ca2a24341ed
Source dataset
uspto-grants-2007_10
Patent number
US07288528B2

Reaction notes

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