Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|
| Edukt | Chlorotrimethylsilane | HCID 6397 | — |
| Edukt | Benzophenone, 2-hydroxy-4'-methoxy- | HCID 87768 | — |
| Edukt | Sodium cyanoborohydride | HCID 5003444 | — |
| Lösungsmittel | Acetonitrile | HCID 6342 | — |
| Lösungsmittel | Dichloromethane | HCID 6344 | — |
| Produkt | 2-(4-Methoxybenzyl)phenol | HCID 258451 | — |
Reaktionsschritte
0.78 g of (2-hydroxyphenyl)(4-methoxyphenyl)methanone is dissolved in acetonitrile and cooled to 0° C. 2 ml of TMSCl are added dropwise to the mixture, and then 1 g of sodium cyanoborohydride is added. The mixture is stirred at room temperature for 3 h. The reaction solution is diluted with dichloromethane and filtered through Celite.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patentnummer | US07288528B2 |
|---|
| Quelldatensatz | uspto-grants-2007_10 |
|---|
| ORD ID | ord-6b62814bfb4949bd98a1936ad814fe05 |
|---|
| Quellennotiz | uspto-grants-2007_10 |
|---|
