HuagongsheHuagongshe Chemistry Print Report · For research reference only
[Methyl-(toluene-4-sulfonyl)-amino]-acetic acid → N-(toluene-4-sulfonyl)sarcosyl-Nepsilon-Boc-L-lysine methyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | [Methyl-(toluene-4-sulfonyl)-amino]-acetic acid | HCID 802555 | — |
| Reactant | L-Lysine, N6-[(1,1-dimethylethoxy)carbonyl]-, methyl ester, hydrochloride (1:1) | HCID 16218818 | — |
| Product | N-(toluene-4-sulfonyl)sarcosyl-Nepsilon-Boc-L-lysine methyl ester | HCID 54444302 | — |
Reaction Steps
N-(Toluene-4-sulfonyl)sarcosine was coupled to Nε-Boc-L-lysine methyl ester hydrochloride using the procedure described in Method 3 to give N-(toluene-4-sulfonyl)sarcosyl-Nε-Boc-L-lysine methyl ester. The title compound was prepared via hydrolysis of the methyl ester using LiOH in THF/water.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07288526B2 |
| Source dataset | uspto-grants-2007_10 |
| ORD ID | ord-4009f3eb1220403a906047aa1b2c050e |
| Source note | uspto-grants-2007_10 |