HCID 69133294, compound → HCID 12109204, compound

Participants

Reaction Steps

A suspension of 3,6-di[(5-benzyloxypyridin-2-yl)methylidene]piperazine-2,5-dione (Compound 10; 0.2 g) and excess of zinc powder in a mixture of 10 mL of acetic acid and 10 mL of water was stirred and refluxed for 5-10 minutes and filtered while hot. Water was added to dissolve zinc acetate. The filtrate was concentrated and filtered. The solid thus obtained was collected and washed with water to give 80 mg (40%) of the desired 3,6-di[(5-benzyloxypyridin-2-yl)methyl]piperazine-2,5-dione (Compound 13).

Provenance & Evidence