HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethylene → 7-Bromo-2-tetralone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethylene | HCID 6325 | — |
| Reactant | (3-Bromophenyl)acetic acid | HCID 74653 | — |
| Product | 7-Bromo-2-tetralone | HCID 3691574 | — |
Reaction Steps
Scheme 3 illustrates a route to 7-substituted tetralin derivative 8. 3-Bromophenylacetic acid is converted to the corresponding acid chloride and this is subjected to Friedel-Crafts reaction with ethene, affording the 7-bromo-2-tetralone 7. This intermediate may be elaborated using the procedures described in Scheme 1 to provide the acid (8).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07288559B2 |
| Source dataset | uspto-grants-2007_10 |
| ORD ID | ord-a5830f6f9ca545779a31d1557ff886ed |
| Source note | uspto-grants-2007_10 |