HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Methylanthranilic acid → HCID 10110562, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Methylanthranilic acid | HCID 75316 | — |
| Reactant | 1,3-Propanediamine, N'-(ethylcarbonimidoyl)-N,N-dimethyl-, monohydrochloride | HCID 2723939 | — |
| Reactant | (2-phenyl-1H-indol-3-yl)acetic acid | HCID 3982630 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 10110562 | HCID 10110562 | 20.9% |
Reaction Steps
2-Phenyl-3-indole acetic acid (0.166 g), 1-(3-dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride (0.127 g) and 4-methylanthranilic acid (0.100 g) in dichloromethane (20 ml) were refluxed for 48 h under nitrogen. The solvent was then removed and the residue purified using mass spectroscopy directed automated HPLC to afford the title compound (0.053 g). LC/MS TR 3.58 min, MH+ 384.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07288564B2 |
| Source dataset | uspto-grants-2007_10 |
| ORD ID | ord-7b0a70ae73784d6cb5d44831a41e207c |
| Source note | uspto-grants-2007_10 |