HuagongsheHuagongshe Chemistry Print Report · For research reference only
Isopropanol → HCID 69424771, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Isopropanol | HCID 3776 | — |
| Reactant | Ethyl Acetate | HCID 8857 | — |
| Reactant | Potassium hydroxy sulfite | HCID 23707502 | — |
| Reactant | HCID 69423988 | HCID 69423988 | — |
| Solvent | Water | HCID 962 | — |
| Product | HCID 69424771 | HCID 69424771 | — |
Reaction Steps
A solution of 5-(3-benzyloxycarbonylamino-2-oxo-pyrrolidin-1-yl)-4-isopropylsulfanylmethyloctahydro-cyclopenta[c]pyrrole-2-carboxylic acid tert-butyl ester in isopropanol is treated with a solution of oxone in water. The reaction mixture is stirred at room temperature until the reaction is complete, and then water and ethyl acetate are added. The organic layer is separated, dried over sodium sulfate and concentrated under vacuum providing the title product.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07288563B2 |
| Source dataset | uspto-grants-2007_10 |
| ORD ID | ord-e944bd5af02f460dafaccce2b2db6718 |
| Source note | uspto-grants-2007_10 |