反应详情

A 500 ml 4-necked round-bottom flask equipped with thermometer and magnetic stirrer, under nitrogen atmosphere, is loaded with 80 g of N-(3-chloro-2-propenyl)-N-methyl-1-naphthalenemethanamine (325 mmoles) (E/Z=80/20) and 317 g of methanol at room temperature. The resulting solution is added with 29.3 g of oxalic acid (325 mmoles), keeping stirring for 15′, then the precipitate is filtered and the product is washed with methanol on the filter. 94.0 g of N-(3-chloro -2-propenyl)-N-methyl-1-naphthalene-methanamine oxalate (279.9 mmoles) are obtained, 86% (E/Z=80/20) molar yield.

1. customA 500 ml 4-necked round-bottom flask equipped with thermometer and magnetic stirrer, under nitrogen atmosphere
2. filtrationis filtered
3. washthe product is washed with methanol on the filter