HuagongsheHuagongshe Chemistry Print Report · For research reference only
(2S)-2-{[(tert-butoxy)carbonyl]amino}-3-(4-iodophenyl)propanoic acid → 4-[(s)-2-Tert-butoxycarbonylamino-3-(4-iodo-phenyl)-propionyl]-piperazine-1-carboxylic acid butyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (2S)-2-{[(tert-butoxy)carbonyl]amino}-3-(4-iodophenyl)propanoic acid | HCID 2755956 | — |
| Reactant | Butyl piperazine-1-carboxylate | HCID 21963126 | — |
| Product | 4-[(s)-2-Tert-butoxycarbonylamino-3-(4-iodo-phenyl)-propionyl]-piperazine-1-carboxylic acid butyl ester | HCID 66770153 | — |
Reaction Steps
This compound was prepared using a method analogous to that of Example 8, step 8.5 Boc-Phe(4-I)-OH replacing 2-phenoxyphenylboronic acid and piperazine-1-carboxylic acid butyl ester replacing intermediate 8.4.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08664203B2 |
| Source dataset | uspto-grants-2014_03 |
| ORD ID | ord-fe8bae641c0844f3abfd2eda1fa19f69 |
| Source note | uspto-grants-2014_03 |