Sodium ethoxide → HCID 58118496, compound

Participants

Reaction Steps

600 mg (1.7 mmol) 7-bromo-2,4-dichloro-9-methoxy-5H-pyrimido[5,4-b]indole was suspended in 20 ml ethanol and mixed with 174 mg (2.6 mmol) sodium ethylate. The mixture was refluxed for 3 h. Having cooled down to room temperature, the solvent was concentrated and water was added. The resulting precipitate was sucked off and washed with water. 450 mg (73%) 7-bromo-2-chloro-4-ethoxy-9-methoxy-5H-pyrimido[5,4-b]indole was obtained. ESI-MS [m/z]: 354, 356 [M−H]−

Provenance & Evidence