Methyl morpholine oxide → HCID 68730500, compound

Participants

Reaction Steps

A solution of the 3α:3β mixture of 4α-acetoxyandrostan-3,17β-diol (380 mg), TPAP (38 mg), NMO (383 mg) under N2 in DCM (15 ml) was stirred in the presence of 4 Å molecular sieves (540 mg) for 1 h. The mixture was filtered and the filtrate was purified by flash chromatography (SiO2, n-hexane/EtOAc 7/3) to give the title compound (353 mg, 93%).

Provenance & Evidence