反应详情

Analogously to the preparation of Example 20, 60 mg (0.2 mmol) of 2-chloro-6-(4-fluorophenyl)-4-(trifluoromethyl)pyridine-3-carbonitrile and 59.5 mg (0.24 mmol) of 6-(piperidin-3-ylamino)pyridine-3-carbonitrile hydrochloride (Example 10A) were used to obtain, after separation by means of preparative HPLC (method 13), 61 mg (66% of theory) of the product in solid form.

1. customto obtain
2. customafter separation by means of preparative HPLC (method 13), 61 mg (66% of theory) of the product in solid form