Acetic Acid → HCID 68748209, compound

Participants

Reaction Conditions

Reaction Steps

The product of Example 2 (200 mg) was mixed with tetrahydro-4H-pyran-4-one (45 mg), NaHB(OAc)3 (96 mg) and HOAc (42 mg) in DCM (5 ml). The reaction mixture was stirred at 30° C. overnight. Saturated NaHCO3 (20 ml) was added to the reaction and the solution was further extracted with EtOAc twice. The combined organic layer was washed with water, brine and dried over Na2SO4. The solution was evaporated and purified by preparative TLC plate to give the titled compound. Mass: (M+1), 659

Provenance & Evidence