1169976-85-5 → HCID 66577742, compound
Reaction equation
[Br:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[O:12][N:11]=[C:10]([CH3:13])[C:9]=2[C:14]([OH:16])=O)=[CH:4][CH:3]=1.Cl.[Cl:18][C:19]1[CH:20]=[C:21]([S:26]([N:29]2[CH2:34][CH2:33][NH:32][CH2:31][CH2:30]2)(=[O:28])=[O:27])[CH:22]=[CH:23][C:24]=1[Cl:25]>>[Br:1][C:2]1[CH:3]=[CH:4][C:5]([C:8]2[O:12][N:11]=[C:10]([CH3:13])[C:9]=2[C:14]([N:32]2[CH2:31][CH2:30][N:29]([S:26]([C:21]3[CH:22]=[CH:23][C:24]([Cl:25])=[C:19]([Cl:18])[CH:20]=3)(=[O:27])=[O:28])[CH2:34][CH2:33]2)=[O:16])=[CH:6][CH:7]=1Participants
3
Procedure
Prepared according to the procedure described in Example 2, Step 1, using 5-(4-bromo-phenyl)-3-methyl-isoxazole-4-carboxylic acid and 1-[(3,4-dichlorophenyl)sulfonyl]piperazine hydrochloride.
Workup
- customPrepared
Sources & evidence
- ORD record
- ord-7c4f6ac3261b4956b7c6191f5b768d11
- Source dataset
- uspto-grants-2014_03
- Patent number
- US08664220B2
Reaction notes
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