2-Oxazolidinone, 4-phenyl-, (4S)- → HCID 66577595, compound

HRID 1183287Notes

Reaction equation

HRID 1183287 reaction equation
[CH2:1]([O:3][C:4]([C:6]1([C:9]2[CH:14]=[CH:13][C:12]([C:15]3[CH:20]=[CH:19][C:18]([C:21]4[O:25][N:24]=[C:23]([CH3:26])[C:22]=4[CH2:27]Br)=[CH:17][CH:16]=3)=[CH:11][CH:10]=2)[CH2:8][CH2:7]1)=[O:5])[CH3:2].[C:29]1([C@H:35]2[CH2:39][O:38][C:37](=[O:40])[NH:36]2)[CH:34]=[CH:33][CH:32]=[CH:31][CH:30]=1>>[CH2:1]([O:3][C:4]([C:6]1([C:9]2[CH:14]=[CH:13][C:12]([C:15]3[CH:20]=[CH:19][C:18]([C:21]4[O:25][N:24]=[C:23]([CH3:26])[C:22]=4[CH2:27][N:36]4[C@@H:35]([C:29]5[CH:34]=[CH:33][CH:32]=[CH:31][CH:30]=5)[CH2:39][O:38][C:37]4=[O:40])=[CH:17][CH:16]=3)=[CH:11][CH:10]=2)[CH2:8][CH2:7]1)=[O:5])[CH3:2]

Participants

3

Reactant 2

HCID 7304242-Oxazolidinone, 4-phenyl-, (4S)-HCID 665771991-[4'-(4-Bromomethyl-3-methyl-isoxazol-5-yl)-biphenyl-4-yl]-cyclopropanecarboxylic acid ethyl ester

Product 1

HCID 66577595HCID 66577595, compound

Procedure

Prepared according to the procedure described in Example 5, Step 3, using 1-[4′-(4-bromomethyl-3-methyl-isoxazol-5-yl)-biphenyl-4-yl]-cyclopropanecarboxylic acid ethyl ester and (S)-4-phenyl-oxazolidin-2-one.

Workup

  1. customPrepared

Sources & evidence

ORD record
ord-bde3c741f09347da8e713dd7d30aee36
Source dataset
uspto-grants-2014_03
Patent number
US08664220B2

Reaction notes

Loading…