Ethyl 1-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)cyclopropanecarboxylate → HCID 66577690, compound

HRID 1183304Notes

Reaction equation

HRID 1183304 reaction equation
[CH2:1]([C:8]1[O:9][C:10]([C:13]2[C:14]([CH3:25])=[N:15][O:16][C:17]=2[C:18]2[CH:23]=[CH:22][C:21](Br)=[CH:20][CH:19]=2)=[N:11][N:12]=1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[CH2:26]([O:28][C:29]([C:31]1([C:34]2[CH:39]=[CH:38][C:37](B3OC(C)(C)C(C)(C)O3)=[CH:36][CH:35]=2)[CH2:33][CH2:32]1)=[O:30])[CH3:27]>>[CH2:26]([O:28][C:29]([C:31]1([C:34]2[CH:39]=[CH:38][C:37]([C:21]3[CH:22]=[CH:23][C:18]([C:17]4[O:16][N:15]=[C:14]([CH3:25])[C:13]=4[C:10]4[O:9][C:8]([CH2:1][C:2]5[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=5)=[N:12][N:11]=4)=[CH:19][CH:20]=3)=[CH:36][CH:35]=2)[CH2:32][CH2:33]1)=[O:30])[CH3:27]

Participants

3

Reactant 2

HCID 53217182Ethyl 1-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)cyclopropanecarboxylateHCID 66577754HCID 66577754, compound

Product 1

HCID 66577690HCID 66577690, compound

Procedure

Prepared according to the procedure described in Example 1, Step 10, using 2-benzyl-5-[5-(4-bromo-phenyl)-3-methyl-isoxazol-4-yl]-[1,3,4]oxadiazole and 1-[4-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-phenyl]-cyclopropanecarboxylic acid ethyl ester.

Workup

  1. customPrepared

Sources & evidence

ORD record
ord-c7c48b9ccc96497c83e7de05f177c72f
Source dataset
uspto-grants-2014_03
Patent number
US08664220B2

Reaction notes

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