HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1183328Generated: November 1, 2026
Ethanol → [1-(4-Bromo-phenyl)-cyclopropyl]-acetic acid ethyl ester
https://huagongshe.com/reaction/1183328
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Ethanol | HCID 702 | — |
| Reactant | Sulfuric Acid | HCID 1118 | — |
| Reactant | 2-[1-(4-Bromophenyl)cyclopropyl]acetic acid | HCID 66577622 | — |
| Product | [1-(4-Bromo-phenyl)-cyclopropyl]-acetic acid ethyl ester | HCID 66577718 | — |
Reaction Steps
[1-(4-Bromo-phenyl)-cyclopropyl]-acetic acid (from the previous step) was dissolved in EtOH (80 mL) and conc. H2SO4 (2 mL) was added. The reaction was heated to 80° C. overnight then concentrated and submitted to standard aqueous workup to afford the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US08664220B2 |
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| Source dataset | uspto-grants-2014_03 |
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| ORD ID | ord-603146772fe34e7e816b5673d55d91b2 |
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| Source note | uspto-grants-2014_03 |
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