HRID1183329

反应详情

EQUATION

反应方程式

REACTANTS

反应物

结构：CCOC(=O)CC1(c2ccc(B3OC(C)(C)C(C)(C)O3)cc2)CC1

HCID66578040

未命名化合物

结构：Cc1noc(-c2ccc(Br)cc2)c1C(O)C/C=C/c1ccc(Cc2ccccc2)cc1

HCID66581369

未命名化合物

PRODUCTS

生成物

结构：CCOC(=O)CC1(c2ccc(-c3ccc(-c4onc(C)c4C(O)C/C=C/c4ccc(Cc5ccccc5)cc4)cc3)cc2)CC1

HCID66581235

未命名化合物

PROCEDURE

实验过程

Prepared according to the procedure described in Example 28, Step 1, using (E)-4-(4-benzyl-phenyl)-1-[5-(4-bromo-phenyl)-3-methyl-isoxazol-4-yl]-but-3-en-1-ol and {1-[4-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-phenyl]-cyclopropyl}-acetic acid ethyl ester.

WORKUP

后处理

customPrepared

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-2e3cbaca40014296aff90b3e982d9059
来源数据集: uspto-grants-2014_03
DOI: 10.6084/m9.figshare.5104873.v1
专利: US08664220B2
来源说明: uspto-grants-2014_03

反应 SMILES

[CH2:1]([C:8]1[CH:13]=[CH:12][C:11](/[CH:14]=[CH:15]/[CH2:16][CH:17]([C:19]2[C:20]([CH3:31])=[N:21][O:22][C:23]=2[C:24]2[CH:29]=[CH:28][C:27](Br)=[CH:26][CH:25]=2)[OH:18])=[CH:10][CH:9]=1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[CH2:32]([O:34][C:35](=[O:55])[CH2:36][C:37]1([C:40]2[CH:45]=[CH:44][C:43](B3OC(C)(C)C(C)(C)O3)=[CH:42][CH:41]=2)[CH2:39][CH2:38]1)[CH3:33]>>[CH2:32]([O:34][C:35](=[O:55])[CH2:36][C:37]1([C:40]2[CH:41]=[CH:42][C:43]([C:27]3[CH:26]=[CH:25][C:24]([C:23]4[O:22][N:21]=[C:20]([CH3:31])[C:19]=4[CH:17]([OH:18])[CH2:16]/[CH:15]=[CH:14]/[C:11]4[CH:10]=[CH:9][C:8]([CH2:1][C:2]5[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=5)=[CH:13][CH:12]=4)=[CH:29][CH:28]=3)=[CH:44][CH:45]=2)[CH2:38][CH2:39]1)[CH3:33]