[5-(4-Bromo-phenyl)-3-methyl-isoxazol-4-yl]-{1-methyl-2-[4-(4-trifluoromethyl-benzyloxy)-phenyl]-ethyl}-amine → {1-[4'-(3-Methyl-4-{1-methyl-2-[4-(4-trifluoromethyl-benzyloxy)-phenyl]-ethylamino}-isoxazol-5-yl)-biphenyl-4-yl]-cyclopropyl}-acetic acid ethyl ester

Participants

Reaction Steps

Prepared according to the procedure described in Example 42, Step 2, using [5-(4-bromo-phenyl)-3-methyl-isoxazol-4-yl]-{1-methyl-2-[4-(4-trifluoromethyl-benzyloxy)-phenyl]-ethyl}-amine and {1-[4-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-phenyl]-cyclopropyl}-acetic acid ethyl ester.

Provenance & Evidence