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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1183367Generated: October 26, 2026

3-[4'-(4-Formyl-3-methyl-isoxazol-5-yl)-biphenyl-4-yl]-propionic acid ethyl ester → 3-{4'-[4-(1-Hydroxy-prop-2-ynyl)-3-methyl-isoxazol-5-yl]-biphenyl-4-yl}-propionic acid ethyl ester

https://huagongshe.com/reaction/1183367

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-[4'-(4-Formyl-3-methyl-isoxazol-5-yl)-biphenyl-4-yl]-propionic acid ethyl esterHCID 86679093—
ReactantHCID 178418486HCID 178418486—
Product3-{4'-[4-(1-Hydroxy-prop-2-ynyl)-3-methyl-isoxazol-5-yl]-biphenyl-4-yl}-propionic acid ethyl esterHCID 86679094—

Reaction Steps

Prepared according to the procedure described in Example 25, Step 1, using 3-[4′-(4-formyl-3-methyl-isoxazol-5-yl)-biphenyl-4-yl]-propionic acid ethyl ester and ethynylmagnesium bromide.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08664220B2
Source datasetuspto-grants-2014_03
ORD IDord-5f803568faaf496abcfe8a292862088b
Source noteuspto-grants-2014_03