Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1183382Generated: November 1, 2026

{1-[4-(4,4,5,5-Tetramethyl-[1,3,2]dioxaborolan-2-yl)-phenyl]cyclopropyl}-acetic acid ethyl ester → [1-(4'-{4-[(5-Benzyl-[1,3,4]oxadiazol-2-yl)-(tert-butyl-dimethyl-silanyloxy)-methyl]-3-methyl-isoxazol-5-yl}-biphenyl-4-yl)-cyclopropyl]-acetic acid ethyl ester

https://huagongshe.com/reaction/1183382

Reaction equation

Participants

RoleNameHCIDCharge
Reactant{1-[4-(4,4,5,5-Tetramethyl-[1,3,2]dioxaborolan-2-yl)-phenyl]cyclopropyl}-acetic acid ethyl esterHCID 66578040—
Reactant2-Benzyl-5-[[5-(4-bromo-phenyl)-3-methyl-isoxazol-4-yl]-(tert-butyl-dimethyl-silanyloxy)-methyl]-[1,3,4]oxadiazoleHCID 66579897—
Product[1-(4'-{4-[(5-Benzyl-[1,3,4]oxadiazol-2-yl)-(tert-butyl-dimethyl-silanyloxy)-methyl]-3-methyl-isoxazol-5-yl}-biphenyl-4-yl)-cyclopropyl]-acetic acid ethyl esterHCID 66580413—

Reaction Steps

Prepared according to the procedure described in Example 1, Step 10, using 2-benzyl-5-[[5-(4-bromo-phenyl)-3-methyl-isoxazol-4-yl]-(tert-butyl-dimethyl-silanyloxy)-methyl]-[1,3,4]oxadiazole and {1-[4-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-phenyl]-cyclopropyl}-acetic acid ethyl ester.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08664220B2
Source datasetuspto-grants-2014_03
ORD IDord-e85fccd08f7b466e8ddb58e996e8b043
Source noteuspto-grants-2014_03