Ethanone, 1-[(1R,2R)-2-phenylcyclopropyl]-, rel- (9CI) → HCID 66581384, compound

HRID 1183390Notes

Reaction equation

HRID 1183390 reaction equation
[Br:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[O:12][N:11]=[C:10]([CH3:13])[C:9]=2[NH2:14])=[CH:4][CH:3]=1.[C:15]1([C@@H:21]2[CH2:23][C@H:22]2[C:24](=O)[CH3:25])[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=1>>[Br:1][C:2]1[CH:3]=[CH:4][C:5]([C:8]2[O:12][N:11]=[C:10]([CH3:13])[C:9]=2[NH:14][CH:24]([C@@H:22]2[CH2:23][C@H:21]2[C:15]2[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=2)[CH3:25])=[CH:6][CH:7]=1

Participants

3

Reactant 2

HCID 6993787Ethanone, 1-[(1R,2R)-2-phenylcyclopropyl]-, rel- (9CI)HCID 582185375-(4-Bromophenyl)-3-methylisoxazol-4-amine

Product 1

HCID 66581384HCID 66581384, compound

Procedure

Prepared according to the procedure described in Example 1, Step 12, using 5-(4-bromo-phenyl)-3-methyl-isoxazol-4-ylamine and trans-1-(2-phenyl-cyclopropyl)-ethanone.

Workup

  1. customPrepared

Sources & evidence

ORD record
ord-cbe4e09fbcb843809c185409d89c1d68
Source dataset
uspto-grants-2014_03
Patent number
US08664220B2

Reaction notes

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