2-Phenyl-1,3-thiazole-5-carbaldehyde → HCID 66577758, compound

HRID 1183440Notes

Reaction equation

HRID 1183440 reaction equation
[CH2:1]([O:3][C:4]([C:6]1([C:9]2[CH:14]=[CH:13][C:12]([C:15]3[CH:20]=[CH:19][C:18]([C:21]4[O:25][N:24]=[C:23]([CH3:26])[C:22]=4[NH2:27])=[CH:17][CH:16]=3)=[CH:11][CH:10]=2)[CH2:8][CH2:7]1)=[O:5])[CH3:2].[C:28]1([C:34]2[S:35][C:36]([CH:39]=O)=[CH:37][N:38]=2)[CH:33]=[CH:32][CH:31]=[CH:30][CH:29]=1>>[CH2:1]([O:3][C:4]([C:6]1([C:9]2[CH:10]=[CH:11][C:12]([C:15]3[CH:20]=[CH:19][C:18]([C:21]4[O:25][N:24]=[C:23]([CH3:26])[C:22]=4[NH:27][CH2:39][C:36]4[S:35][C:34]([C:28]5[CH:29]=[CH:30][CH:31]=[CH:32][CH:33]=5)=[N:38][CH:37]=4)=[CH:17][CH:16]=3)=[CH:13][CH:14]=2)[CH2:8][CH2:7]1)=[O:5])[CH3:2]

Participants

3

Reactant 2

HCID 27637062-Phenyl-1,3-thiazole-5-carbaldehydeHCID 665771951-[4'-(4-Amino-3-methyl-isoxazol-5-yl)-biphenyl-4-yl]-cyclopropanecarboxylic acid ethyl ester

Product 1

HCID 66577758HCID 66577758, compound

Procedure

Prepared according to the procedure described in Example 1, Step 12, using 1-[4′-(4-amino-3-methyl-isoxazol-5-yl)-biphenyl-4-yl]-cyclopropanecarboxylic acid ethyl ester and 2-phenyl-thiazole-5-carbaldehyde.

Workup

  1. customPrepared

Sources & evidence

ORD record
ord-f24e2db0adc248b08fc435e1e2401d85
Source dataset
uspto-grants-2014_03
Patent number
US08664220B2

Reaction notes

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