2-Bromo-6-phenylpyridine → HCID 66581321, compound

HRID 1183485Notes

Reaction equation

HRID 1183485 reaction equation
[CH2:1]([O:3][C:4](=[O:27])[C:5]([C:8]1[CH:13]=[CH:12][C:11]([C:14]2[CH:19]=[CH:18][C:17]([C:20]3[O:24][N:23]=[C:22]([CH3:25])[C:21]=3[NH2:26])=[CH:16][CH:15]=2)=[CH:10][CH:9]=1)([CH3:7])[CH3:6])[CH3:2].Br[C:29]1[CH:34]=[CH:33][CH:32]=[C:31]([C:35]2[CH:40]=[CH:39][CH:38]=[CH:37][CH:36]=2)[N:30]=1>>[CH2:1]([O:3][C:4](=[O:27])[C:5]([CH3:7])([C:8]1[CH:13]=[CH:12][C:11]([C:14]2[CH:19]=[CH:18][C:17]([C:20]3[O:24][N:23]=[C:22]([CH3:25])[C:21]=3[NH:26][C:29]3[CH:34]=[CH:33][CH:32]=[C:31]([C:35]4[CH:36]=[CH:37][CH:38]=[CH:39][CH:40]=4)[N:30]=3)=[CH:16][CH:15]=2)=[CH:10][CH:9]=1)[CH3:6])[CH3:2]

Participants

3

Reactant 2

HCID 5686792-Bromo-6-phenylpyridineHCID 66577785HCID 66577785, compound

Product 1

HCID 66581321HCID 66581321, compound

Procedure

Prepared according to the procedure described in Example 134, Step 3, using 2-[4′-(4-amino-3-methyl-isoxazol-5-yl)-biphenyl-4-yl]-2-methyl-propionic acid ethyl ester and 2-bromo-6-phenyl-pyridine.

Workup

  1. customPrepared

Sources & evidence

ORD record
ord-87dfbee9b64d474d9da1279af4876a08
Source dataset
uspto-grants-2014_03
Patent number
US08664220B2

Reaction notes

Loading…