HuagongsheHuagongshe Chemistry Print Report · For research reference only
Triethylamine → HCID 86679096, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | 2,6-Dibromopyridine | HCID 12274 | — |
| Reactant | Cyclopentylacetylene | HCID 136725 | — |
| Catalyst | Copper(1+) iodide; Copper(I) iodide; Cuprous iodide; Cuprous iodide (CuI) | HCID 24350 | — |
| Catalyst | HCID 178418476 | HCID 178418476 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 86679096 | HCID 86679096 | — |
Reaction Steps
2,6-Dibromo-pyridine (0.544 g, 2.34 mmol), cyclopentylacetylene (0.220 g, 2.34 mmol), copper(I) iodide (0.445 g, 2.34 mmol), triethylamine (0.98 mL, 7.01 mmol) and bis(triphenylphosphine)palladium(II) dichloride (0.164 g, 0.023 mmol) were combined in DMF and stirred at room temperature for 2 days. The reaction was purified via silica gel chromatography to afford the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08664220B2 |
| Source dataset | uspto-grants-2014_03 |
| ORD ID | ord-3b31c7222da2400689f4d3f1d8d1eab4 |
| Source note | uspto-grants-2014_03 |