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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1183500Generated: October 27, 2026

4-Ethoxycarbonylphenylboronic acid → 4'-[3-Methyl-4-(5-phenyl-[1,3,4]oxadiazol-2-ylamino)-isoxazol-5-yl]-biphenyl-4-carboxylic acid ethyl ester

https://huagongshe.com/reaction/1183500

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Ethoxycarbonylphenylboronic acidHCID 2734350—
Reactant[5-(4-Bromo-phenyl)-3-methyl-isoxazol-4-yl]-(5-phenyl-[1,3,4]oxadiazol-2-yl)-amineHCID 66577739—
Product4'-[3-Methyl-4-(5-phenyl-[1,3,4]oxadiazol-2-ylamino)-isoxazol-5-yl]-biphenyl-4-carboxylic acid ethyl esterHCID 66579252—

Reaction Steps

Prepared according to the procedure described in Example 42, Step 2, using [5-(4-bromo-phenyl)-3-methyl-isoxazol-4-yl]-(5-phenyl-[1,3,4]oxadiazol-2-yl)-amine and 4-ethoxycarbonylphenylboronic acid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08664220B2
Source datasetuspto-grants-2014_03
ORD IDord-7c991a98b75340658ebe12efac80d23f
Source noteuspto-grants-2014_03