3,5-Dibromopyridine → 3-Bromo-5-(2,5-difluorophenyl)pyridine

HRID 1183522Notes

Reaction equation

HRID 1183522 reaction equation
Br[C:2]1[CH:3]=[N:4][CH:5]=[C:6]([Br:8])[CH:7]=1.[F:9][C:10]1[CH:15]=[CH:14][C:13]([F:16])=[CH:12][C:11]=1B(O)O>>[Br:8][C:6]1[CH:5]=[N:4][CH:3]=[C:2]([C:14]2[CH:15]=[C:10]([F:9])[CH:11]=[CH:12][C:13]=2[F:16])[CH:7]=1

Participants

3

Reactant 2

HCID 693693,5-DibromopyridineHCID 2734335(2,5-Difluorophenyl)boronic acid

Product 1

HCID 529370453-Bromo-5-(2,5-difluorophenyl)pyridine

Procedure

Prepared according to the procedure described in Example 48, Step 2, using 3,5-dibromo-pyridine and 2,5-difluorophenylboronic acid.

Workup

  1. customPrepared

Sources & evidence

ORD record
ord-16861484e38041bb816ec9fc306b0fe3
Source dataset
uspto-grants-2014_03
Patent number
US08664220B2

Reaction notes

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