Bis(eta-cyclopentadienyl) iron → HCID 178520619, compound

Participants

Reaction Steps

In a specific embodiment, a silylferrocene compound such as 4-(dimethylsilyl)butylferrocene can be prepared. The process for the preparation of 4-(dimethylsilyl)butylferrocene comprises (a) treating ferrocene with 4-chlorobutyryl chloride, in the presence of aluminum chloride catalyst and an organic solvent to obtain the acylated product, 4-chlorobutyroylferrocene; (b) reduction of 4-chlorobutyroylferrocene to yield 4-chlorobutylferrocene, using without limitation a Clemmensen type reduction; (c) treating 4-chlorobutylferrocene with a metal such as a magnesium under Grignard reaction conditions to form the corresponding Grignard intermediate compound which when reacted with chlorodimethylsilane in-situ yields 4-(dimethylsilyl)butylferrocene.

Provenance & Evidence