HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-fluoro-N-(4-methoxybutyl)-6-nitroaniline → 3-Fluoro-2-(4-methoxybutylamino)aniline
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-fluoro-N-(4-methoxybutyl)-6-nitroaniline | HCID 58355288 | — |
| Catalyst | HCID 178418390 | HCID 178418390 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | 3-Fluoro-2-(4-methoxybutylamino)aniline | HCID 58355280 | 98.3% |
Reaction Steps
2-Fluoro-N-(4-methoxybutyl)-6-nitroaniline (3.54 g) was dissolved in methanol (50 ml), palladium-carbon (5%, 140 mg) was added, and the mixture was stirred for 3.5 hr under a hydrogen atmosphere. The reaction mixture was filtered through celite, and the filtrate was concentrated under reduced pressure to give the object product (3.05 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08664380B2 |
| Source dataset | uspto-grants-2014_03 |
| ORD ID | ord-df680b6b141e43319733a60a85e32dba |
| Source note | uspto-grants-2014_03 |