HuagongsheHuagongshe Chemistry Print Report · For research reference only
Trifluoroacetic acid → HCID 85189178, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Trifluoroacetic acid | HCID 6422 | — |
| Reactant | tert-Butyl 17-bromo-4,7,10,13-tetraoxaheptadec-15-en-1-oate | HCID 53399024 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 85189178 | HCID 85189178 | 98.8% |
Reaction Steps
At RT, a solution of 1 g of 3-(2-{2-[2-(4-bromo-but-2-enyloxy)-ethoxy]-ethoxy}-ethoxy)-propionic acid tert-butyl ester (commercially available), 6 ml of TFA and 3 ml of DCM is stirred during 3 hrs, and then concentrated to dryness under RP. The oily residue is diluted with toluene and concentrated to dryness under RP affording 853 mg of 3-(2-{2-[2-(4-bromo-but-2-enyloxy)-ethoxy]-ethoxy}-ethoxy)-propionic acid in the form of a brown oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08668910B2 |
| Source dataset | uspto-grants-2014_03 |
| ORD ID | ord-e50903a50cdf4bbfb7f7e6ef1db14eda |
| Source note | uspto-grants-2014_03 |