HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-(Furan-2-yl)-2-oxopropanoic acid → 8-benzyl-2-(furan-2-ylmethyl)-6-phenyl-7H-imidazo[1,2-a]pyrazin-3-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-(Furan-2-yl)-2-oxopropanoic acid | HCID 2049778 | — |
| Reactant | 2-Amino-3-benzyl-5-phenylpyrazine | HCID 10214659 | — |
| Product | 8-benzyl-2-(furan-2-ylmethyl)-6-phenyl-7H-imidazo[1,2-a]pyrazin-3-one | HCID 178515641 | — |
Reaction Steps
Synthesized from method C using 3-(furan-2-yl)-2-oxopropanoic acid and 3-benzyl-5-phenylpyrazin-2-amine as starting materials. 1H NMR (300 MHz, dmso) δ 8.88 (s, 1H), 8.02 (d, J=7.9, 2H), 7.61-7.38 (m, 6H), 7.37-7.14 (m, 3H), 6.38 (s, 1H), 6.26 (d, J=3.2, 1H), 4.64 (s, 3H), 4.40 (s, 3H); exact mass calculated for C24H20N3O2+ m/z+382.16, found m/z+382.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08669103B2 |
| Source dataset | uspto-grants-2014_03 |
| ORD ID | ord-292b6755b67145b4b2a84aef072ae750 |
| Source note | uspto-grants-2014_03 |