HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-OXO-3-(2-THIENYL)PROPANOIC ACID → 8-benzyl-6-phenyl-2-(thiophen-2-ylmethyl)-7H-imidazo[1,2-a]pyrazin-3-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-OXO-3-(2-THIENYL)PROPANOIC ACID | HCID 2049780 | — |
| Reactant | 2-Amino-3-benzyl-5-phenylpyrazine | HCID 10214659 | — |
| Product | 8-benzyl-6-phenyl-2-(thiophen-2-ylmethyl)-7H-imidazo[1,2-a]pyrazin-3-one | HCID 178515662 | — |
Reaction Steps
Synthesized from method C using 2-oxo-3-(thiophen-2-yl)propanoic acid and 3-benzyl-5-phenylpyrazin-2-amine as starting materials. 1H NMR (300 MHz, dmso) δ 8.85 (s, 1H), 7.99 (d, J=6.8, 2H), 7.63-7.02 (m, 10H), 6.94 (dd, J=3.5, 5.1, 1H), 4.62 (s, 2H), 4.58 (s, 2H), 2.69 (contaminate); exact mass calculated for C24H20N3OS+ m/z+398.13, found m/z+398.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08669103B2 |
| Source dataset | uspto-grants-2014_03 |
| ORD ID | ord-6dcab653e3694cadac03acaef7e96d96 |
| Source note | uspto-grants-2014_03 |