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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1184328Generated: October 26, 2026

4-Hydroxyphenylpyruvic Acid → 8-cyclopropyl-2-[(4-hydroxyphenyl)methyl]-6-phenyl-7H-imidazo[1,2-a]pyrazin-3-one

https://huagongshe.com/reaction/1184328

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Hydroxyphenylpyruvic AcidHCID 979—
Reactant3-Cyclopropyl-5-phenylpyrazin-2-amineHCID 67494385—
Product8-cyclopropyl-2-[(4-hydroxyphenyl)methyl]-6-phenyl-7H-imidazo[1,2-a]pyrazin-3-oneHCID 178515645—

Reaction Steps

Synthesized using method A with 3-cyclopropyl-5-phenylpyrazin-2-amine and 3-(4-hydroxyphenyl)-2-oxopropanoic acid as starting materials. Exact mass calculated for C22H18N3O2+ m/z−356.14, found m/z−356.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08669103B2
Source datasetuspto-grants-2014_03
ORD IDord-18155ac5c9cd4315bf651cc5302ea9d9
Source noteuspto-grants-2014_03