Pyruvic aldehyde dimethyl acetal → 8-benzyl-2-methyl-6-phenyl-7H-imidazo[1,2-a]pyrazin-3-one

HRID 1184329Notes

Reaction equation

HRID 1184329 reaction equation
C[O:2][CH:3](OC)[C:4](=O)[CH3:5].[CH2:9]([C:16]1[C:17]([NH2:28])=[N:18][CH:19]=[C:20]([C:22]2[CH:27]=[CH:26][CH:25]=[CH:24][CH:23]=2)[N:21]=1)[C:10]1[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=1>>[CH2:9]([C:16]1[NH:21][C:20]([C:22]2[CH:23]=[CH:24][CH:25]=[CH:26][CH:27]=2)=[CH:19][N:18]2[C:3](=[O:2])[C:4]([CH3:5])=[N:28][C:17]=12)[C:10]1[CH:11]=[CH:12][CH:13]=[CH:14][CH:15]=1

Participants

3

Reactant 2

HCID 80650Pyruvic aldehyde dimethyl acetalHCID 102146592-Amino-3-benzyl-5-phenylpyrazine

Product 1

HCID 1784320758-benzyl-2-methyl-6-phenyl-7H-imidazo[1,2-a]pyrazin-3-one

Procedure

Synthesized using method B with 1,1-dimethoxypropan-2-one and 3-benzyl-5-phenylpyrazin-2-amine as starting materials. Exact mass calculated for C20H18N30+ m/z+316.14, found m/z+316.

Workup

  1. customSynthesized

Sources & evidence

ORD record
ord-0d044a1a5b9e45fe843379a59c62a566
Source dataset
uspto-grants-2014_03
Patent number
US08669103B2

Reaction notes

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