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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1184355Generated: October 26, 2026

Dihydro-8-methyl-2H-1,4-benzoxazine-2-carboxamide → Dihydro-8-methyl-2H-1,4-benzoxazine-2-methanamine

https://huagongshe.com/reaction/1184355

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDihydro-8-methyl-2H-1,4-benzoxazine-2-carboxamideHCID 67497427—
ReactantDihydro-8-fluoro-2H-1,4-benzoxazine-2-methanamineHCID 67497870—
ProductDihydro-8-methyl-2H-1,4-benzoxazine-2-methanamineHCID 67498071—

Reaction Steps

This compound is obtained using the same experimental conditions as those used for the synthesis of intermediate 2b but by replacing 3,4-dihydro-8-fluoro-2H-1,4-benzoxazine-2-carboxamide (4b) with 3,4-dihydro-8-methyl-2H-1,4-benzoxazine-2-carboxamide (4c). The title compound of formula (2c) is obtained.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08669250B2
Source datasetuspto-grants-2014_03
ORD IDord-bb69e053b920402581cdc48e7e79ae79
Source noteuspto-grants-2014_03