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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1184357Generated: October 26, 2026

Dihydro-8-chloro-2H-1,4-benzoxazine-2-carboxamide → Dihydro-8-chloro-2H-1,4-benzoxazine-2-methanamine

https://huagongshe.com/reaction/1184357

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDihydro-8-chloro-2H-1,4-benzoxazine-2-carboxamideHCID 67496535—
ReactantDihydro-8-fluoro-2H-1,4-benzoxazine-2-methanamineHCID 67497870—
ProductDihydro-8-chloro-2H-1,4-benzoxazine-2-methanamineHCID 67496530—

Reaction Steps

This compound is obtained following the same experimental conditions as those used for the synthesis of intermediate 2b but replacing 3,4-dihydro-8-fluoro-2H-1,4-benzoxazine-2-carboxamide (4b) with 3,4-dihydro-8-chloro-2H-1,4-benzoxazine-2-carboxamide (4d). The title compound of formula (2d) is obtained.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08669250B2
Source datasetuspto-grants-2014_03
ORD IDord-4643b0c15f2f4f228b1d2ac5f3c84c40
Source noteuspto-grants-2014_03