HuagongsheHuagongshe Chemistry Print Report · For research reference only
Phenol → HCID 71813140, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Phenol | HCID 996 | — |
| Reactant | 4-Hydroxy-3-nitrobenzaldehyde | HCID 18169 | — |
| Reactant | Butanoic acid, 2-bromo-, methyl ester | HCID 95577 | — |
| Product | HCID 71813140 | HCID 71813140 | — |
Reaction Steps
Using 4-hydroxy-3-nitrobenzaldehyde as the phenol and methyl-2-bromobutanoate as the alkylating agent in the general procedure of alkylation of substituted 2-nitrophenols gives a clear yellow oil: 1H NMR (DMSO-d6, 400 MHz): δ=9.94 (s, 1H), 8.44 (d, J=2.3 Hz, 1H), 8.13 (dd, J=8.8, 2.0 Hz, 1H), 7.42 (d, J=8.8 Hz, 1H), 5.36 (dd, J=6.6, 4.5 Hz, 1H), 3.70 (s, 3H), 1.88-2.05 (m, 2H), 0.98 ppm (t, J=7.5 Hz, 3H). ESI-MS: m/z 268.2 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08669249B2 |
| Source dataset | uspto-grants-2014_03 |
| ORD ID | ord-09081b6cd0a942d3be2891974a88e68a |
| Source note | uspto-grants-2014_03 |