Phenol → HCID 86664209, compound

Participants

Reaction Steps

Using 4-hydroxy-3-methyl-5-nitrobenzaldehyde as the phenol and methyl-2-bromopropanoate as the alkylating agent in the general procedure of alkylation of substituted 2-nitrophenols gives a light tan solid: 1H NMR (400 MHz, DMSO-d6) δ ppm 1.49-1.56 (m, 3H) 2.42 (s, 3H) 3.62 (s, 3H) 4.82 (q, J=6.82 Hz, 1H) 8.10 (d, J=1.52 Hz, 1H) 8.29 (d, J=1.52 Hz, 1H) 9.98 (s, 1H). ESI-MS: m/z 268.2 (M+H)+.

Provenance & Evidence