HCID 59416781, compound → 3-Fluoro-N-isopropyl-4-(piperazin-1-yl)benzamide

Participants

Reaction Steps

tert-butyl 4-(2-fluoro-4-(isopropylcarbamoyl)phenyl)piperazine-1-carboxylate 303 (1.10 g, 3.01 mmol) was diluted with 4.0M HCl in dioxane (3 mL) and stirred for 30 min. The thick white precipitate that formed was diluted with ethyl ether (10 mL) and stirred until a fine suspension resulted. The precipitate was filtered under nitrogen and dried in vacuum to afford the title compound as a white solid. ESI-MS: m/z 302 (M+H)+.

Provenance & Evidence