Phenol → HCID 86664214, compound

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Reaction Steps

Using 4-hydroxy-2-methyl-3-nitrobenzaldehyde as the phenol and methyl-2-bromopropanoate as the alkylating agent in the general procedure for alkylation of substituted-2-nitrophenols gives the title compound as a white solid: 1H NMR (400 MHz, DMSO-d6) δ ppm 1.51 (d, J=6.82 Hz, 3 H) 2.50 (s, 3H) 3.69 (s, 3H) 5.40 (q, J=6.82 Hz, 1H) 7.29 (d, J=9.09 Hz, 1H) 8.00 (d, J=8.84 Hz, 1H) 10.12 (s, 1H). ESI-MS: m/z 268.2 (M+H)+.

Provenance & Evidence