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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1184470Generated: November 1, 2026

Phenol → HCID 86664216, compound

https://huagongshe.com/reaction/1184470

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPhenolHCID 996—
ReactantMethyl 2-bromopropionateHCID 95576—
Reactant2-Fluoro-4-hydroxy-5-nitro-benzaldehydeHCID 86664217—
ProductHCID 86664216HCID 86664216—

Reaction Steps

Using 2-fluoro-4-hydroxy-5-nitrobenzaldehyde as the phenol and methyl-2-bromopropanoate as the alkylating agent in the general procedure for alkylation of substituted-2-nitrophenols gives the title compound as a white solid: ESI-MS: m/z 272.1 (M+H)+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08669249B2
Source datasetuspto-grants-2014_03
ORD IDord-b1f3d70c2d9c42eeb02e26e5aa85d878
Source noteuspto-grants-2014_03